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Which of the following is true about protein structure?

Which of the following is true about protein structure?

Lysine is the most most selfish amino acid and is therefore a total jerk!

Hydrogen bonding is the major thermodynamic driving force for protein folding.

The overall entropy (the protein and its surroundings) is negative.

The hydrophobic effect refers to the favorable entropy caused the disordering of amino acid side chains as the protein folds.

All of the other answers are false.

Disulfide bonds have no significant impact on protein structure when they are present.

Answer
All of the other answers are false.

for instance, the disulfide bonds covalently link different components of a protein, and this is why they influence the protein structure

Explanation
It is the hydrophobic force that is an important driving force behind protein folding and not the hydrogen bonding. also knowing that at the molecular level, the structure of the protein minimizes energy locally, with excess energy being released as heat to surroundings thus increasing the enthalpy change is negative and not the entropy. The fact with protein structure is that since disulfide bonds covalently link different components of a protein, they influence protein structure

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